Breast Cancer Genetics Study Dubbed 'Giant Step' - WBOC-TV 16, Delmarvas News Leader, FOX 21 -

Breast Cancer Genetics Study Dubbed 'Giant Step'

Posted:
(Photo: AP) (Photo: AP)

NEW YORK (AP)— Scientists reported Sunday that they have completed a major analysis of the genetics of breast cancer, finding four major classes of the disease. They hope their work will lead to more effective treatments, perhaps with some drugs already in use.

The new finding offers hints that one type of breast cancer might be vulnerable to drugs that already work against ovarian cancer. 

The study, published online Sunday by the journal Nature, is the latest example of research into the biological details of tumors, rather than focusing primarily on where cancer arises in the body. 

The hope is that such research can reveal cancer's genetic weaknesses for better drug targeting. 

"With this study, we're one giant step closer to understanding the genetic origins of the four major subtypes of breast cancer," Dr. Matthew Ellis of the Washington University School of Medicine said in a statement. He is a co-leader of the research. 

"Now we can investigate which drugs work best for patients based on the genetic profiles of their tumors," he said.

The researchers analyzed DNA of breast cancer tumors from 825 patients, looking for abnormalities. Altogether, they reported, breast cancers appear to fall into four main classes when viewed in this way. 

One class showed similarities to ovarian cancers, suggesting it may be driven by similar biological developments. 

"It's clear they are genetically more similar to ovarian tumors than to other breast cancers," Ellis said. "Whether they can be treated the same way is an intriguing possibility that needs to be explored." 

The report is the latest from the Cancer Genome Atlas, a federally funded project that has produced similar analyses for brain, colorectal, lung, and ovarian cancers.

  • Most Popular StoriesMost Popular StoriesMore>>

  • One Killed, Another Injured in Millsboro Crash

    One Killed, Another Injured in Millsboro Crash

    Wednesday, April 23 2014 7:42 AM EDT2014-04-23 11:42:43 GMT
    Delaware State Police say one woman was killed and another woman was injured in a Tuesday night crash in Millsboro.More
    Delaware State Police say one woman was killed and another woman was injured in a Tuesday night crash in Millsboro.More
  • Two People Critically Injured in Sussex County Crash

    Two People Critically Injured in Sussex County Crash

    Tuesday, April 22 2014 11:24 PM EDT2014-04-23 03:24:31 GMT
    MILLSBORO, De - Delaware State Police say Bank Road in Millsboro is closed following a two-vehicle collision that occurred around 9 p.m. this evening. Police say two people were removed from the scene of the accident and are being treated for critical injuries. Troopers are still investigating this motor vehicle accident in Sussex County.More
    MILLSBORO, De - Delaware State Police say Bank Road in Millsboro is closed following a two-vehicle collision that occurred around 9 p.m. this evening. Police say two people were removed from the scene of the accident and are being treated for critical injuries. Troopers are still investigating this motor vehicle accident in Sussex County.More
  • Millsboro Man Arrested for Concealing Marijuana in His Mouth

    Millsboro Man Arrested for Concealing Marijuana in His Mouth

    Wednesday, April 23 2014 10:22 AM EDT2014-04-23 14:22:04 GMT
    BISHOPVILLE, Md. – The passenger in a car stopped for speeding was caught concealing marijuana in his mouth.More
    Authorities in Worcester County say a Millsboro, Del., man who was a passenger in a car stopped for speeding, was caught concealing marijuana in his mouth. More
Powered by WorldNow

All content © Copyright 2000 - 2014 Worldnow and WBOC. All Rights Reserved. For more information on this site, please read our Privacy Policy and Terms of Service