Gene mutation tied to higher obesity risk in kids - WBOC-TV 16, Delmarvas News Leader, FOX 21 -

Gene mutation tied to higher obesity risk in kids

Updated:
  • HealthMore>>

  • The 'Hobby Lobby ruling' and what it means for U.S. health care

    The 'Hobby Lobby ruling' and what it means for U.S. health care

    The U.S. Supreme Court's ruling on contraception coverage -- as mandated under the Affordable Care Act -- could lead to a legal quagmire that might allow companies to deny insurance coverage for any medical practice that violates their religious principles.More
    The U.S. Supreme Court's ruling on contraception coverage -- as mandated under the Affordable Care Act -- could lead to a legal quagmire that might allow companies to deny insurance coverage for any medical practice that violates their religious principles.More
  • Diet changes can alter gut bacteria

    Diet changes can alter gut bacteria

    Dietary changes can dramatically alter the balance of bacteria in the gut on a daily basis, according to a new study.More
    Dietary changes can dramatically alter the balance of bacteria in the gut on a daily basis, according to a new study.More
  • Lift U.S. ban on blood donations by gay men

    Lift U.S. ban on blood donations by gay men

    The United States should repeal a 30-year policy that bans blood donations from gay and bisexual men, according to a team of medical and legal experts writing this week in the Journal of the American Medical...More
    The United States should repeal a 30-year policy that bans blood donations from gay and bisexual men, according to a team of medical and legal experts writing this week in the Journal of the American Medical Association.More

THURSDAY, Oct. 24 (HealthDay News) -- Obesity is on the rise among children, and a particular genetic mutation might play a role for some kids, a new study suggests.

Researchers in Britain conducted genetic analyses of more than 2,100 severely obese youngsters. They found that those with mutations in the KSR2 gene had larger appetites and slower metabolism than those with a normal copy of the gene, according to the study published in the Oct. 24 issue of the journal Cell.

"Changes in diet and levels of physical activity underlie the recent increase in obesity; however, some people gain weight more easily than others," study author Sadaf Farooqi, of the University of Cambridge, noted in a journal news release. "This variation between people is largely influenced by genetic factors. The discovery of a new obesity gene, KSR2, demonstrates that genes can contribute to obesity by reducing metabolic rate -- how well the body burns calories."

The findings could someday lead to new treatments for obesity and type 2 diabetes, the researchers said.

Farooqi and colleagues had previously found that deleting the KSR2 gene led to obesity in mice, highlighting the gene's role in controlling energy balance and metabolism. These findings confirm KSR2's role in the regulation of weight and metabolism in humans.

"This work adds to a growing body of evidence that genes play a major role in influencing a person's weight and may be useful for developing new ways to treat people who are heavy and develop diabetes," Farooqi said.

More information

The American Academy of Pediatrics has more about childhood obesity.

Copyright © 2013 HealthDay. All rights reserved.

*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.
Powered by WorldNow

All content © Copyright 2000 - 2014 Worldnow and WBOC. All Rights Reserved. For more information on this site, please read our Privacy Policy and Terms of Service