The state elections board says voter turnout for Tuesday's elections was about 21 percent, not including absentee and provisional ballots.
Republican Sen. David Brinkley, who is the Senate minority leader, lost his primary bid to Del. Michael Hough in western Maryland.
In Baltimore, Democratic Del. Keiffer Mitchell and Del. Melvin Stukes both lost in a district that had been reconfigured in legislative redistricting to only one House seat instead of three.
On the Eastern Shore, Republican Sen. Richard Colburn lost to Del. Adelaide Eckardt.
Cecil County Republican Del. Michael Smigiel lost his primary race as well.
Democratic Del. Luiz Simmons lost his primary bid for a Montgomery County Senate seat to former Del. Cheryl Kagan.
For more results from Tuesday's primary, click here.