New twice-daily formula combines pumpkin seed oil, beta-sitosterol, lycopene, broccoli sprout extract and pygeum, with an ingredient-by-ingredient research overview
AURORA, Colo., Sept. 19, 2026 — Zenith Labs today announced the U.S. launch of TitanFlow, its five-ingredient capsule supplement for men’s daily urinary and prostate wellness. The formula combines a seed oil, a plant sterol, an antioxidant carotenoid, a cruciferous vegetable extract and a traditional botanical, in a twice-daily capsule formulated with the intent of supporting normal urinary flow and urethral tissue function in adult men over forty. It is designed for men who want a single daily supplement that fits into an established routine of balanced nutrition, physical activity and regular healthcare.
The formula contains pumpkin seed oil, beta-sitosterol, lycopene, broccoli sprout extract and pygeum (Prunus africanum) bark extract. The recommended serving is two capsules daily, ideally taken with the first meal. Each bottle contains a 30-day supply. Zenith Labs states that TitanFlow is produced in an FDA-inspected U.S. facility following strict quality standards and undergoes independent testing.
Alongside the launch, Zenith Labs is publishing an ingredient overview that summarizes published research on each component. The overview also explains where that research stops and what it does not establish about the finished product.
“Men’s urinary wellness supplements are often sold on bold promises built from loosely connected studies,” said Ryan Shelton, Creator of Zenith Labs. “We took the opposite approach. TitanFlow is a straightforward daily formula, and we’re telling consumers exactly what’s in it, what the science on each ingredient actually shows, and where the evidence is still limited.”
A Multi-Ingredient Formula for Daily Men’s Urinary and Prostate Wellness
TitanFlow formula draws from four ingredient categories, each associated with different aspects of normal physiological function:
- Seed oil: Pumpkin seed oil supplies fatty acids and plant sterols that have been studied in the context of normal urinary flow and urethral tissue support, though findings from individual ingredient studies do not establish outcomes for the finished formula.
- Plant sterol: Beta-sitosterol is a naturally occurring phytosterol found in pumpkin seeds and many other plant foods, recognized for its research history in the context of normal bladder emptying and urinary flow.
- Antioxidant carotenoid: Lycopene is a dietary antioxidant found in tomatoes and other red-pigmented produce, studied for its relationship to normal prostate cell health and oxidative protection of urinary tract tissue.
- Botanical extracts: Broccoli sprout extract and pygeum bark extract contribute naturally occurring plant compounds that have been studied in the context of antioxidant support, normal inflammatory balance and smooth muscle tone in the urinary tract, based on research into isolated ingredients rather than the finished formula.
The combination reflects the company’s view that men’s urinary and prostate wellness involves multiple systems — including urethral tissue integrity, smooth muscle tone, antioxidant protection and normal inflammatory balance — rather than a single pathway. Zenith Labs emphasizes that this is a formulation rationale, not a clinical finding. The finished product has not been evaluated as a complete formula in published clinical trials.
Pumpkin Seed Oil: Research on Urinary Flow and Urethral Support
Pumpkin seed (Cucurbita pepo) oil is derived from the seeds of the pumpkin and has a recognized history of use in European traditional medicine for urinary and bladder health. It is rich in unsaturated fatty acids, tocopherols and plant sterols — including delta-7-sterols — that are not found in the same concentrations in most other seed oils. These compounds have been studied for their relationship to normal urethral tissue integrity and bladder function.
A randomized, double-blind, placebo-controlled trial published in the Journal of Traditional and Complementary Medicine examined pumpkin seed oil supplementation in men and women with overactive bladder symptoms and observed improvements in urinary frequency and bladder capacity scores compared with placebo over 12 weeks. A separate small pilot study in healthy men noted improvements in certain urinary flow metrics following daily pumpkin seed oil supplementation over a similar period; pilot studies are preliminary in nature and their findings require confirmation in larger, more rigorously controlled trials.
These studies had important limits — specific doses, defined populations, controlled conditions — and their findings describe how the oil interacts with urinary function markers, not outcomes from the finished TitanFlow formula.
Full details regarding ingredient specifications are provided in the company’s product documentation.
Beta-Sitosterol: Research on Bladder Emptying and Urinary Flow
Beta-sitosterol is one of the most abundant phytosterols in the human diet, found in pumpkin seeds, nuts, vegetable oils and many plant foods. Phytosterols are structurally similar to cholesterol and are thought to compete with it at absorption sites in the intestine, influencing downstream hormonal and inflammatory signaling. Beta-sitosterol has one of the most studied research histories of any plant compound in the context of men’s lower urinary tract symptoms.
A meta-analysis of randomized controlled trials published in the Lancet examined beta-sitosterol supplementation in men with lower urinary tract symptoms associated with benign prostatic hyperplasia and observed statistically significant improvements in urinary symptom scores, urinary flow rates and residual urine volume compared with placebo. The reviewers noted that while findings were consistent across studies, trials were of relatively short duration, most participants had a diagnosed clinical condition, and the long-term effects in general adult populations remained less clearly established.
These findings are limited to specific doses of isolated beta-sitosterol in defined populations. They describe how the compound interacts with urinary function markers and do not demonstrate outcomes from TitanFlow, which contains beta-sitosterol alongside four other ingredients.
Lycopene: Research on Antioxidant Activity and Prostate Health Markers
Lycopene is a carotenoid pigment responsible for the red color of tomatoes, watermelon and certain other fruits. It is among the dietary carotenoids most studied for antioxidant properties and has attracted scientific interest for its relationship to normal prostate cell health. Lycopene has been observed to accumulate in prostate tissue at relatively higher concentrations than in many other tissues, making it a recognized compound of interest in men’s prostate wellness research — though the clinical significance of this accumulation is not yet fully established.
A body of epidemiological research has associated higher dietary lycopene intake with lower risk of certain prostate-related conditions in population studies. A systematic review and meta-analysis examining lycopene supplementation and prostate health markers observed associations between lycopene intake and changes in PSA levels and prostate tissue oxidative stress markers in specific study populations. These associations are observational in nature; PSA level alone is not a definitive measure of prostate health, and the studies did not demonstrate causal relationships between lycopene supplementation and prostate outcomes.
These studies had important limits. Epidemiological associations do not establish causation, and intervention studies examined specific lycopene doses in defined populations. Their findings describe lycopene’s antioxidant relationship to prostate tissue markers and do not demonstrate outcomes from TitanFlow, which contains lycopene alongside four other ingredients. Its inclusion reflects the recognized antioxidant profile of lycopene and the active scientific interest in its prostate-related compounds, not a product-specific clinical claim.
Broccoli Sprout Extract: A Cruciferous Source of Antioxidant Compounds
Broccoli sprouts (Brassica oleracea) are an exceptionally concentrated source of glucoraphanin, a glucosinolate compound that is converted in the body to sulforaphane — one of the most studied naturally occurring antioxidant and cytoprotective compounds in nutrition science. Sulforaphane activates the Nrf2 pathway, a key cellular defense mechanism that upregulates antioxidant enzymes and supports normal inflammatory balance in tissues throughout the body, including the urogenital tract.
Laboratory and animal studies have examined sulforaphane extensively in the context of antioxidant protection of epithelial cells, normal cellular detoxification and inflammatory modulation. Human clinical evidence on broccoli sprout extract supplementation specifically for urinary wellness is more limited in volume and methodological consistency, and a 2020 Cochrane systematic review on botanical extracts across a range of chronic outcomes noted that evidence for many plant preparations remained insufficient to support therapeutic claims, citing small study sizes and inconsistent outcome measures.
Broccoli sprout extract’s inclusion in TitanFlow reflects its recognized role as an antioxidant source and its complementary contribution to the formula’s cellular protection rationale, rather than a product-specific clinical claim.
Pygeum: A Traditional Botanical With Urinary Smooth Muscle Research
Pygeum (Prunus africanum), also known as African cherry, is an evergreen tree native to sub-Saharan Africa whose bark has been used in traditional African medicine for urinary complaints for centuries. Its bioactive compounds include phytosterols, pentacyclic triterpenoids and ferulic acid esters, which have been studied for their relationship to normal smooth muscle relaxation in the lower urinary tract and normal prostate tissue health.
A Cochrane systematic review of randomized controlled trials examining pygeum bark extract in men with lower urinary tract symptoms found that, in the context of the included studies, men taking pygeum were more likely to report improvement in overall urinary symptoms compared with placebo. The review noted improvements in self-reported nocturia, peak urinary flow and residual urine volume across studies. However, the reviewers identified important limitations: most included trials were of short duration, used varying pygeum preparations and doses, and were of modest methodological quality — limiting the strength of conclusions that can be drawn.
These findings describe responses to specific pygeum preparations in defined populations and do not establish outcomes from TitanFlow, which contains pygeum alongside four other ingredients. Its inclusion reflects pygeum’s recognized traditional use history and the body of clinical research interest in its urinary smooth muscle compounds.
What Ingredient Research Does and Does Not Show
TitanFlow research overview separates three questions: what each ingredient is, what researchers have studied about it, and what has been demonstrated about the finished formula. Those questions have different answers.
The studies referenced here examined individual ingredients at specific doses, in specific populations and over specific periods. TitanFlow combines five ingredients in a twice-daily capsule, and the amounts, preparations and interactions within that formula differ from the conditions of any individual study. For that reason, Zenith Labs does not describe TitanFlow as clinically proven and does not attribute ingredient-level research results to the finished product.
“We think men respond better to honesty than hype,” said Ryan Shelton. “Every ingredient in TitanFlow has a legitimate nutritional role or an active research history. What we won’t do is stretch a study beyond what it found.”
Safety and Suitability
TitanFlow is intended for healthy adult men. Men who are taking prescription medication, particularly those for blood pressure, cholesterol or anticoagulation, should consult a qualified healthcare professional before use, as beta-sitosterol and pygeum have each been associated with potential interactions with specific medications. The same consultation applies to men who are managing a medical condition, scheduled for surgery or taking other dietary supplements.
Consumers should follow the directions on the product label and should not exceed the recommended serving. The physical label and Supplement Facts panel are the definitive source for ingredient amounts, directions and warnings.
Product Format and Availability
TitanFlow is available now to consumers across the United States through the official Zenith Labs website. The formula is delivered as a capsule, with the recommended serving of two capsules daily taken with the first meal. The product is produced in an FDA-inspected U.S. facility following strict quality standards and undergoes independent third-party testing.
FDA inspection of a manufacturing facility relates to production standards and quality controls. It does not indicate FDA approval of the product or its claims, as dietary supplements are not approved by the FDA before sale.
About Zenith Labs and TitanFlow
Zenith Labs was founded with the conviction that evidence-informed wellness supplements should be built around transparency — disclosing every ingredient, explaining the research behind each one accurately and acknowledging the limits of that research with equal clarity.
The company’s mission is to develop formulas that target specific physiological systems with credible, well-sourced ingredients, manufactured to the highest quality standards in the United States. Every Zenith Labs product is developed in collaboration with healthcare practitioners, formulated from ingredients with published research histories and produced in an FDA-inspected facility that undergoes independent quality testing.
TitanFlow represents that mission applied to men’s daily urinary and prostate wellness — a category the company believes has been poorly served by products that focus narrowly on prostate size while overlooking the broader physiology of normal urinary flow. The TitanFlow formula is designed to nutritionally support urethral tissue health, smooth muscle tone, antioxidant protection and normal inflammatory balance through a combination of five well-sourced ingredients, based on the research profiles of those individual ingredients rather than clinical evaluation of the finished formula.
TitanFlow flagship formula combines pumpkin seed oil, beta-sitosterol, lycopene, broccoli sprout extract and pygeum bark extract in a twice-daily capsule. More information is available at prostaterevealed.com.
References
- Nishimura M, Ohkawara T, Sato H, et al. Pumpkin seed oil extracted from Cucurbita maxima improves urinary disorder in human overactive bladder. Journal of Traditional and Complementary Medicine. 2014;4(1):72–74.
- Wilt TJ, MacDonald R, Ishani A. Beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU International. 1999;83(9):976–983.
- Giovannucci E. Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature. Journal of the National Cancer Institute. 1999;91(4):317–331.
- Fahey JW, Zhang Y, Talalay P. Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proceedings of the National Academy of Sciences. 1997;94(19):10367–10372.
- Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. American Journal of Medicine. 2000;109(8):654–664.
- Robertson NU, Schoonees A, Brand A, Visser J. Pine bark (Pinus spp.) extract for treating chronic disorders. Cochrane Database of Systematic Reviews. 2020;9:CD008294.
Media Contact
Ryan Shelton, Creator
Zenith Labs, TitanFlow
19655, E 35th Drive Suite 100 Aurora, CO 80011
Email: Support@ZenithLabs.com
Phone: (800) 928-1184
Website: prostaterevealed.com
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Research cited here concerns individual ingredients only and does not constitute clinical evaluation of the complete TitanFlow
formula or endorsement by the cited researchers, journals or agencies.
The post TitanFlow Reviews: Zenith Labs® Launches Five-Ingredient Daily Capsule Supplement for Men’s Urinary and Prostate Wellness in the U.S. appeared first on 24 Health Times.
